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Bosutinib, sold
under the
brand name Bosulif, is a
small molecule BCR-ABL and src
tyrosine kinase inhibitor used for the
treatment of
chronic myelogenous...
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Bosutinib's activity was
first described in 2001 and it was
disclosed as an Abl
kinase inhibitor in 2003. At
first it was
believed that
bosutinib was...
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approved in
South Korea for
people resistant to or
intolerant of imatinib.
Bosutinib received US FDA and EU
European Medicines Agency approval on 4 September...
- (ALK) Non-receptor bcr-abl
Asciminib Bosutinib Dasatinib Imatinib Nilotinib Ponatinib Radotinib Src (
Bosutinib Dasatinib) J****
kinase Baricitinib Fedratinib...
- (ALK) Non-receptor bcr-abl
Asciminib Bosutinib Dasatinib Imatinib Nilotinib Ponatinib Radotinib Src (
Bosutinib Dasatinib) J****
kinase Baricitinib Fedratinib...
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Sunitinib (Sutent)
Dasatinib (Sprycel)
Lapatinib (Tykerb)
Nilotinib (Tasigna)
Bosutinib (Bosulif)
Ponatinib (Iclusig)
Asciminib (Scemblix)
Bortezomib (Velcade)...
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Other tyrosine kinase inhibitor drugs that are in
clinical trials include bosutinib, bafetinib, Saracatinib(AZD-0530), XLl-999, KX01 and XL228. HSP90 inhibitor...
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injectables such as the EpiPen. On
September 4, 2012, the FDA
approved bosutinib (Bosulif) for
chronic myelogenous leukemia (CML), a rare type of leukemia...
- for "Study of
Efficacy of CML-CP
Patients Treated With ABL001
Versus Bosutinib,
Previously Treated With 2 or More TKIs" at ClinicalTrials.gov Portal:...
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available inhibitors to
treat CML are imatinib, dasatinib, nilotinib,
bosutinib and ponatinib.
Gastrointestinal stromal tumors (GIST) are
known to withstand...