-
Bivalirudin, sold
under the
brand names Angiomax and Angiox,
among others, is a
specific and
reversible direct thrombin inhibitor (DTI). Chemically, it...
- this purpose;
mainly used are danaparoid, fondaparinux, argatroban, and
bivalirudin.
While purified heparin was
first used in
humans in the 1930s, HIT was...
- to
direct thrombin inhibitors including dabigatran, argatroban, and
bivalirudin.
After separating the
plasma from the
whole blood by centrifugation,...
- that
bivalirudin is non-inferior
compared to
heparin and that
bivalirudin is ****ociated with a
lower rate of bleeding.
Unlike the hirudins,
bivalirudin is...
- argatroban.
Other "blood thinners"
sometimes used in this
setting include bivalirudin and fondaparinux.
Platelet transfusions are not
routinely used to treat...
-
members are
already in
clinical use (such as lepirudin, argatroban,
bivalirudin and dabigatran). Also in
clinical use are
other small molecular compounds...
-
desirudin (Revasc/Iprivask) –
differs by
removal of
sulfate group on Tyr63
bivalirudin –
peptide fragment Several other direct thrombin inhibitors are derived...
-
members of this
class include the
bivalent drugs hirudin, lepirudin, and
bivalirudin and the
monovalent drugs argatroban and dabigatran. An oral
direct thrombin...
- example, the
anticoagulant drugs,
hirudin and its
synthetic congener,
bivalirudin, are
based on
saliva chemistry of the leech,
Hirudo medicinalis. Used...
-
thrombocytopenia and
thrombosis require alternative forms of anticoagulation.
Bivalirudin is the most
studied heparin-alternative in
people with heparin-induced...
