- A
bispecific monoclonal antibody (BsMAb, BsAb) is an
artificial protein that can
simultaneously bind to two
different types of
antigen or two different...
- Bi-specific T-cell
engager (BiTE) is a
class of
artificial bispecific monoclonal antibodies that are
investigated for use as anti-cancer drugs. They direct...
- Odronextamab, sold
under the
brand name Ordspono, is a CD20 x CD3
bispecific monoclonal antibody that is used for the
treatment of
follicular lymphoma...
- Tecvayli, is a
human bispecific monoclonal antibody used for the
treatment of
relapsed and
refractory multiple myeloma. It is a
bispecific antibody that targets...
-
brand name Columvi, is a
bispecific monoclonal antibody used for the
treatment of
large B-cell lymphoma. It is a
bispecific CD20-directed CD3 T-cell engager...
- for the
treatment of extensive-stage
small cell lung cancer. It is a
bispecific T-cell
engager that
binds delta-like
ligand 3 and CD3. The most common...
-
commercial manufacturing. The
company focuses on
monoclonal antibodies,
bispecific antibodies, antibody-drug conjugates, and mRNA vaccines. The
company has...
-
Along scFv and Fab fragments,
diabodies or
bispecific recombinant antibodies are the
third major format.
Bispecific antibodies combine two
different antigen...
- Emicizumab, sold
under the
brand name Hemlibra, is a
humanized bispecific monoclonal antibody for the
treatment of
haemophilia A,
developed by Genentech...
- region, thus
obtaining a
bispecific antibody (with both Fab and Fcab
regions containing distinct binding sites).
These bispecific monoclonal antibodies are...
