- A
bispecific monoclonal antibody (BsMAb, BsAb) is an
artificial protein that can
simultaneously bind to two
different types of
antigen or two different...
- Bi-specific T-cell
engager (BiTE) is a
class of
artificial bispecific monoclonal antibodies that are
investigated for use as anti-cancer drugs. They direct...
-
brand name Columvi, is a
bispecific monoclonal antibody used for the
treatment of
large B-cell lymphoma. It is a
bispecific CD20-directed CD3 T-cell engager...
- antigens, in
which case they are
types of
bispecific antibodies. The
furthest developed of
these are
bispecific tandem di-scFvs,
known as bi-specific T-cell...
- Tecvayli, is a
human bispecific monoclonal antibody used for the
treatment of
relapsed and
refractory multiple myeloma. It is a
bispecific antibody that targets...
-
brand name Rybrevant, is a
bispecific monoclonal antibody used to
treat non-small cell lung cancer.
Amivantamab is a
bispecific epidermal growth factor (EGF)...
- for the
treatment of
diffuse large B-cell lymphoma.
Epcoritamab is a
bispecific CD20-directed CD3 T-cell engager.
Epcoritamab was co-developed by AbbVie...
- for the
treatment of extensive-stage
small cell lung cancer. It is a
bispecific T-cell
engager that
binds delta-like
ligand 3 and CD3. The most common...
- Odronextamab, sold
under the
brand name Ordspono, is a CD20 x CD3
bispecific monoclonal antibody that is used for the
treatment of
follicular lymphoma...
- Emicizumab, sold
under the
brand name Hemlibra, is a
humanized bispecific monoclonal antibody for the
treatment of
haemophilia A,
developed by Genentech...
