-
toxicity are also modified. Non-classical
bioisosteres may
differ in a
multitude of ways from
classical bioisosteres, but
retain the
focus on
providing similar...
-
biochemistry and
medicinal chemistry,
phosphonate groups are used as
stable bioisosteres for phosphate, such as in the
antiviral nucleotide analog, Tenofovir...
-
Chemistry of Drug
Design and Drug Action,
Second Edition, 2004
Nathan Brown.
Bioisosteres in
Medicinal Chemistry. Wiley-VCH, 2012, p. 237. ISBN 978-3-527-33015-7...
-
FIGURE 7 |
Benzofuran bioisosteres of tryptamines.
Tomaszewski Z,
Johnson MP,
Huang X,
Nichols DE (May 1992). "Benzofuran
bioisosteres of
hallucinogenic tryptamines"...
-
amphetamine and
benzothiophene families. It is
related to MDA and
other MDA
bioisosteres like the benzofurans. The drug acts as a
potent and well-balanced...
-
Acylsulfonamides are of
particular interest due to
their ability to act as
bioisosteres of
carboxylic acids,
offering similar hydrogen bonding capabilities and...
- MacMillan,
David W. C. (June 2023). "General
access to
cubanes as
benzene bioisosteres". Nature. 618 (7965): 513–518. Bibcode:2023Natur.618..513W. doi:10...
- a
tetrazole which is
being used in
place of the
carboxylic acid as a
bioisostere.
Losartan is used for hypertension,
including in
people with left ventricular...
- ring system-substituted lysergamides: 12-Hydroxy-LSD 12-Methoxy-LSD
Bioisosteres: JRT
Others Arylpiperazines (e.g., 2C-B-PP, 2-NP, mCPP, MK-212, ORG-12962...
- This is a list of
cocaine analogues. A
cocaine analogue is an (usually)
artificial construct of a
novel chemical compound from (often the
starting point...
