-
toxicity are also modified. Non-classical
bioisosteres may
differ in a
multitude of ways from
classical bioisosteres, but
retain the
focus on
providing similar...
-
Chemistry of Drug
Design and Drug Action,
Second Edition, 2004
Nathan Brown.
Bioisosteres in
Medicinal Chemistry. Wiley-VCH, 2012, p. 237. ISBN 978-3-527-33015-7...
-
biochemistry and
medicinal chemistry,
phosphonate groups are used as
stable bioisosteres for phosphate, such as in the
antiviral nucleotide analog, Tenofovir...
- This is a list of
cocaine analogues. A
cocaine analogue is an (usually)
artificial construct of a
novel chemical compound from (often the
starting point...
-
Acylsulfonamides are of
particular interest due to
their ability to act as
bioisosteres of
carboxylic acids,
offering similar hydrogen bonding capabilities and...
- a
tetrazole which is
being used in
place of the
carboxylic acid as a
bioisostere.
Losartan is used for hypertension,
including in
people with left ventricular...
-
FIGURE 7 |
Benzofuran bioisosteres of tryptamines.
Tomaszewski Z,
Johnson MP,
Huang X,
Nichols DE (May 1992). "Benzofuran
bioisosteres of
hallucinogenic tryptamines"...
-
Meanwell NA (March 2011). "Synopsis of Some
Recent Tactical Application of
Bioisosteres in Drug Design".
Journal of
Medicinal Chemistry. 54 (8): 2529–91. doi:10...
- 1]propellane. The bicyclo[1.1.1]pentane
structure has been used as an
unusual bioisostere for a
phenyl ring.
Housane Staffane Wiberg,
Kenneth B.; Walker, Frederick...
-
Tomaszewski Z,
Johnson MP,
Huang X,
Nichols DE (May 1992). "Benzofuran
bioisosteres of
hallucinogenic tryptamines".
Journal of
Medicinal Chemistry. 35 (11):...
