-
Bicuculline is a phthalide-isoquinoline
compound that is a light-sensitive
competitive antagonist of
GABAA receptors. It was
originally identified in...
- It has long been
recognized that, for
neurons that are
stimulated by
bicuculline and picrotoxin, the fast
inhibitory response to GABA is due to direct...
-
binding site for GABA and
several drugs such as muscimol, gaboxadol, and
bicuculline. The
protein also
contains a
number of
different allosteric binding sites...
- was
structurally derived from the
GABAA antagonist bicuculline by a team at Roche.
Unlike bicuculline, ROD-188 acts as an
agonist at
GABAA receptors, being...
-
Heinemann U (April 2007). "Effects of the GABA(A)
receptor antagonists bicuculline and
gabazine on stimulus-induced
sharp wave-ripple
complexes in adult...
- used for
counteracting overdoses of
sedative drugs.
Examples include bicuculline,
securinine and metrazol, and the
benzodiazepine GABAA receptor antagonist...
- the
blood brain barrier and
enter the
brain Bicuculline methiodide, a water-soluble form of
bicuculline Tertiary phosphines and
phosphite esters also...
-
impairing substances, including: ethanol, chlorodiazepoxide, scopolamine,
bicuculline, picrotoxin, and cycloheximide.
Unlike other racetams,
nefiracetam shows...
-
Vigabatrin (y-vinyl-GABA) – anticonvulsant; GABA-T
inhibitor Bamaluzole Bicuculline Deramciclane Ethanol Fengabine Gabapentinoid Loreclezole Propofol Retigabine/ezogabine...
-
Strychnine is a
strong antagonist at
ionotropic glycine receptors,
whereas bicuculline is a weak one.
Glycine is a
required co-agonist
along with glutamate...
