Definition of Autoreactive. Meaning of Autoreactive. Synonyms of Autoreactive

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Definition of Autoreactive

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Meaning of Autoreactive from wikipedia

- hand causes also origin of so called "autoreactive T cells" which recognize self antigens via their TCRs. Autoreactive T cells must be eliminated from the...
- central tolerance, where autoreactive T-cells are killed without being released into circulation. Via a similar mechanism, autoreactive B-cells in the bone...
- in the periphery. Negative selection is not 100% effective, and some autoreactive T cells escape and are released into the circulation. Additional mechanisms...
- developing T or B lymphocytes that are autoreactive, i.e. reactive to the body itself. Through elimination of autoreactive lymphocytes, tolerance ensures that...
- periphery. Dendritic cells (DCs) parti****te in the negative selection of autoreactive T cells in the thymus, but they also mediate peripheral immune tolerance...
- In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8+) lymphocytes that become...
- selected) or a state of anergy is induced to prevent self targeting. Autoreactive T cells must normally be held in check by the suppressive environment...
- negative selection mechanisms to remove potentially self destructing autoreactive T cells. Their "self" antigens are displa**** to a developing T-cell and...
- T-cell receptors, whereas other thymocytes make T-cell receptors that are autoreactive. If a functional T cell receptor is formed, the thymocyte will begin...
- expressing high affinity for self-antigen undergo clonal deletion. If autoreactive cells escape clonal deletion, there are mechanisms in the periphery involving...