-
endosomal membranes to form the prophagop****
termed HyPAS (hybrid pre-
autophagosomal structure). ATG16L1
binding to WIPI2
mediates ATG16L1's activity. This...
-
dominant proteinaceous component, the core
contains mitochondrial and
autophagosomal membrane components,
suggesting a link with
organelle dysfunction. It...
-
generated from Pre-
Autophagosomal Structure (PAS)
which is
distinct from the
precursor structures in
mammalian cells. The pre-
autophagosomal structure in yeast...
-
protein required for the
formation of
autophagosomal membranes. The
transient conjugation of Atg8 to the
autophagosomal membrane through a ubiquitin-like...
- the
Golgi apparatus, chloroplasts, peroxisomes,
plasma membranes,
autophagosomal membranes, and
novel cytoplasmic compartments. The
replication of the...
-
vesicles that do not fuse,
therefore preventing the
formation of the pre-
autophagosomal structure. In
addition to phagop**** ****embly,
SNAREs are also important...
- formation. The
initiation of
autophagy involves the
building of the pre-
autophagosomal structure (PAS). Most Atg
proteins ac****ulate at the PAS and generate...
-
functionally link up with each
other integrating all
processes necessary for
autophagosomal formation: (i) the ULK1-ATG13-FIP200/RB1CC1
complex ****ociates with...
- S,
Lidke KA, Jain A, et al. (November 2021). "Mammalian
hybrid pre-
autophagosomal structure HyPAS generates autophagosomes". Cell. 184 (24): 5950–5969...
- ubiquitin-
proteasome system, UPS,
required for the
unique development of an
autophagosomal membrane and
fusion within cells. ATG7 was
identified based on homology...
