- is
encoded by the WAS gene. In the
inactive state, WASp
exists in an
autoinhibited conformation with
sequences near its C-terminus
binding to a region...
-
AVERAGE STRUCTURE 1tiu: TITIN, IG
REPEAT 27, NMR, 24
STRUCTURES 1tki:
AUTOINHIBITED SERINE KINASE DOMAIN OF THE
GIANT MUSCLE PROTEIN TITIN 1tnm: TERTIARY...
-
Komander D (July 2013). "Structure of the
human Parkin ligase domain in an
autoinhibited state". The EMBO Journal. 32 (15): 2099–112. doi:10.1038/emboj.2013...
- Acid is a
Selective and
Covalent Rab-Prenylation
Inhibitor Targeting Autoinhibited RabGGTase".
Journal of the
American Chemical Society. 134 (17): 7384–7391...
- released,
meaning this
domain is no
longer autoinhibited. However, the CARD and NB-ARC
domains remain in
autoinhibited state. The CARD
domain will only be released...
-
mammalian phenylalanine hydroxylase reveals the
architecture of an
autoinhibited tetramer".
Proceedings of the
National Academy of
Sciences of the United...
-
Ishiyama N, Ho J, Di
Palma V,
Stambolic V,
Ikura M (Sep 2012). "An
autoinhibited noncanonical mechanism of GTP
hydrolysis by Rheb
maintains mTORC1 homeostasis"...
- of the Met Receptor. 1ssl:
Solution structure of the PSI
domain from the Met
receptor 2g15:
Structural Characterization of
autoinhibited c-Met kinase...
- of
water followed by cell
swelling and bursting. Notably, GSDMD-N is
autoinhibited by
GSDMD C-terminal
domain before cleavage to
prevent cell
lysis in...
- ZAP-70
Kinase Domain in
Complex with
Staurosporine 2oq1:
Tandem SH2
domains of ZAP-70 with 19-mer zeta1
peptide 2ozo:
Autoinhibited intact human ZAP-70...
