- Caspase-1,
normally in its
physiologically inactive zymogen form,
autoactivates when it is ****embled into the
filamentous inflammasome complex by autoproteolysis...
- an
inactive zymogen of
trypsin in the pancreas, but
occasionally will
autoactivate itself. PSTI
serves to
cleave prematurely activated trypsin to prevent...
-
opposite direction,
preventing trans-phosphorylation. The agr QS
circuit autoactivates transcription of agrA which, in turn
upregulates the phenol-souble modulins...
- the full-length
receptor ALK dimerizes,
changes conformation, and
autoactivates its own
kinase domain,
which in turn
phosphorylates other ALK receptors...
-
human CLN2 protein/tripeptidyl-peptidase I is a
serine protease that
autoactivates at
acidic pH". The
Journal of
Biological Chemistry. 276 (3): 2249–55...
-
creating the
basic structural elements of the AIM2 inflammasome. Caspase-1
autoactivates and
processes cleavage of pro-IL-1β, pro-IL-18, and
gasdermin D. The...
-
depends on two inputs, the
first being the
ability of many Hox
proteins to
autoactivate their own transcription, and the
second derived from two
large groups...
