- In
molecular biology, the
arfaptin domain is a
protein domain which interacts with ARF1, a
small GTPase involved in
vesicle budding at the
Golgi complex...
-
Arfaptin-2 is a
protein that in
humans is
encoded by the ARFIP2 gene. ARFIP2 has been
shown to
interact with Arf6, ARF3, ARF5 and RAC1. GRCh38: Ensembl...
- S2CID 21106205. Shin OH,
Exton JH (August 2001). "Differential
binding of
arfaptin 2/POR1 to ADP-ribosylation
factors and Rac1".
Biochemical and Biophysical...
-
Rittinger K,
Gamblin SJ, S****on SJ (2001). "The
structural basis of
Arfaptin-mediated cross-talk
between Rac and Arf
signalling pathways". Nature. 411...
- functions.
These include PI3K.
Other small GTPases may bind
adaptors such as
arfaptin or
second messenger systems such as
adenylyl cyclase. The Ras
binding domain...
-
Arfaptin-1 is a
protein that in
humans is
encoded by the ARFIP1 gene. ARFIP1 has been
shown to
interact with ARF3. GRCh38:
Ensembl release 89: ENSG00000164144...
- PMID 9312003. Shin OH,
Exton JH (August 2001). "Differential
binding of
arfaptin 2/POR1 to ADP-ribosylation
factors and Rac1". Biochem. Biophys. Res. Commun...
-
humans is
encoded by the ICA1 gene. This gene
encodes a
protein with an
arfaptin homology domain that is
found both in the
cytosol and as membrane-bound...
- PMID 8836150. Tsai SC,
Adamik R, Hong JX, et al. (1998). "Effects of
arfaptin 1 on
guanine nucleotide-dependent
activation of
phospholipase D and cholera...
-
ANALYSIS OF RAC1-GDP
COMPLEXED WITH
ARFAPTIN (P21) 1i4l:
CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN
COMPLEX WITH
ARFAPTIN (P41) 1i4t:
CRYSTAL STRUCTURE ANALYSIS...
