-
Ansamycins is a
family of
bacterial secondary metabolites that show
antimicrobial activity against many Gram-positive and some Gram-negative bacteria,...
- Rifampicin, also
known as rifampin, is an
ansamycin antibiotic used to
treat several types of
bacterial infections,
including tuberculosis (TB), Mycobacterium...
- ciprofloxacin, the
first 2nd-gen
fluoroquinolone 1987 – rifaximin, the
first ansamycin 1988 –
azithromycin 1988 –
flomoxef 1988 –
isepamycin 1988 – midecamycin...
- site and
binding mode has been characterized. It is a
macrolide of the
ansamycin type and can be
isolated from
plants of the
genus Maytenus. Derivatives...
-
rifamycinica or artificially. They are a
subclass of the
larger family of
ansamycins.
Rifamycins are
particularly effective against mycobacteria, and are therefore...
- The
strain DSM 44262 of
Amycolatopsis alba
produces sesquiterpenes and
ansamycins. Mertz, F. P.; Yao, R. C. (1
October 1993). "Amycolatopsis alba sp. nov...
-
differentiate from tannins. Also
lactams instead of
lactones (as in the
ansamycin family) are excluded.
Included are not only 12-16
membered macrocycles...
-
Geldanamycin is a 1,4-benzoquinone
ansamycin antitumor antibiotic that
inhibits the
function of Hsp90 (Heat
Shock Protein 90) by
binding to the unusual...
-
Herbimycin is a
benzoquinone ansamycin antibiotic that
binds to Hsp90 (Heat
Shock Protein 90) and
alters its function. Hsp90
client proteins play important...
-
Streptomyces sp. RK95-74
isolated from soil in ****an in 1997. Cyt A is an
ansamycin.
Cytotrienin A
induces apoptosis on HL-60 cells, as well as inhibiting...
