-
Amnionless is a
protein that in
humans is
encoded by the AMN gene. A
complex of
amnionless and
cubilin forms the
cubam receptor. The
protein encoded by...
-
located in the
terminal ileum. This
receptor is
composed of two proteins,
amnionless (AMN), and cubilin. A
defect in
either of
these protein components can...
- of
amnionless (AMN), and cubilin.
Cubilin is
essential as a cell
receptor recognizing the "vitamin B12-intrinsic factor" complex,
whereas amnionless is...
- the stomach. IF
delivers the
vitamin to
receptor proteins cubilin and
amnionless,
which together form the
cubam receptor in the
distal ileum. The receptor...
-
neuron (α-MNs),
large lower motor neurons of the
brainstem and
spinal cord
Amnionless, a gene for a
protein necessary for
efficient absorption of
vitamin B12...
- play a role in
autosomal recessive megaloblastic anemia. A
complex of
amnionless and
cubilin forms the
cubam receptor.
Cubilin is a
potential diagnostic...
- Wang X,
Bornslaeger EA, Haub O, et al. (1996). "A
candidate gene for the
amnionless gastrulation stage mouse mutation encodes a TRAF-related protein". Dev...
- transcytosis. LRP2/megalin can also form
complexes with CUBAM, the
cubilin and
amnionless complex.
Those complexes are able to
reabsorb several molecules and can...
- formation/function of the
endocytic complex that also
involves megalin and cubilin/
amnionless receptors, the sodium-hydrogen
antiporter 3 (NHE3), and the V-ATPase....