-
Alrestatin is an
inhibitor of
aldose reductase, an
enzyme involved in the
pathogenesis of
complications of
diabetes mellitus,
including diabetic neuropathy...
- ac****ulates,
causing osmotic damage which leads to
retinopathy and neuropathy.
Alrestatin Epalrestat Fidarestat Imirestat Lidorestat Minalrestat Ponalrestat Ranirestat...
-
alprafenone (INN)
alprazolam (INN)
alprenolol (INN)
alprostadil (INN)
alrestatin (INN)
Alrex alsactide (INN)
Altace (Pfizer/Sanofi-Aventis)
Altamist altanserin...
- naphthalimides,
which are used as
optical brighteners.
Derivatives include:
Alrestatin,... Griesbaum, Karl; Behr, Arno; Biedenkapp, Dieter; Voges, Heinz-Werner;...
- "Inhibition of
human brain aldose reductase and
hexonate dehydrogenase by
alrestatin and sorbinil". J Neurochem. 39 (3): 810–4. doi:10.1111/j.1471-4159.1982...
- the
treatment of
Secondary Acute Myeloid Leukaemia.[citation needed]
Alrestatin Allen SL,
Lundberg AS (July 2011). "Amonafide: a
potential role in treating...
-
available in
several countries.
Additional reductase inhibitors such as
Alrestatin, Exisulind, Imirestat, Zopolrestat, Tolrestat, Zenarestat, Caficrestat...
-
inhibitors include the
acetic acid
compounds zopolrestat, tolrestat,
alrestatin, and epalrestat. Many of
these compounds have not been
successful in clinical...
-
ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN
DIABETIC COMPLICATIONS 1az1:
ALRESTATIN BOUND TO C298A/W219Y
MUTANT HUMAN ALDOSE REDUCTASE 1az2:
CITRATE BOUND...