-
Allysine is a
derivative of
lysine that
features a
formyl group in
place of the
terminal amine. The free
amino acid does not exist, but the
allysine residue...
-
reactive aldehydes and
allysine via
oxidative deamination.
These reactive aldehydes and
allysines can
react with
other lysine and
allysine residues to form...
-
Through saccharopine and
allysine,
lysine is
converted to α-aminoadipate,
which is then
degraded all the way to acetoacetate.
Allysine is
oxidized by...
- cross-linking of
collagen by
inhibiting lysyl oxidase and thus the
formation of
allysine,
leading to
loose skin.
Recent experiments have
attempted to
develop this...
-
catalyzes the
conversion of
lysine residues into its
aldehyde derivative allysine.
Allysine form cross-links in
extracellular matrix proteins.
Inhibition of lysyl...
-
Conversion of some
lysine residues to
allysine occurs first,
followed by
bonding between lysine and
allysine. This
enables the
elastin to form in the...
- lysine→
Saccharopine Allysine α-Aminoadipic acid 2-Oxoadipic acid Glutaryl-CoA Glutaconyl-CoA Crotonyl-CoA β-Hydroxybutyryl-CoA leucine→ β-Hydroxy β-methylbutyric...
- lysine→
Saccharopine Allysine α-Aminoadipic acid 2-Oxoadipic acid Glutaryl-CoA Glutaconyl-CoA Crotonyl-CoA β-Hydroxybutyryl-CoA leucine→ β-Hydroxy β-methylbutyric...
- lysine→
Saccharopine Allysine α-Aminoadipic acid 2-Oxoadipic acid Glutaryl-CoA Glutaconyl-CoA Crotonyl-CoA β-Hydroxybutyryl-CoA leucine→ β-Hydroxy β-methylbutyric...
- acetylation, ubiquitylation, SUMOylation, methylation,
hydroxylation leading to
allysine,
spontaneous isopeptide bond
formation Methionine Met or M N-acetylation...
