- In
organic chemistry,
alkynylation is an
addition reaction in
which a
terminal alkyne (−C≡CH) is
added to a
carbonyl group (C=O) to form an α-alkynyl alcohol...
- SIB-1508Y, also
known as Altinicline, a
nicotinic receptor agonist. The
alkynylation reaction of aryl
halides using aromatic acetylenes was
reported in 1975...
- for
methyl ethers and
methyl amines.
Hydrodealkylation Transalkylation Alkynylation Friedel–Crafts
reaction Category:Alkylating
agents Category:Ethylating...
-
reaction Organolithium reagents Sakurai reaction Indium-mediated
allylation Alkynylation Smith,
Michael B.; March,
Jerry (2007),
Advanced Organic Chemistry: Reactions...
-
reaction a
pyridine zwitterion in the
Hammick reaction an
acetylide in
alkynylation reactions. a
cyanide ion in
cyanohydrin reactions In many nucleophilic...
-
Ariana R.; Smith, Joel M. (2021-09-03). "Regioselective
Asymmetric Alkynylation of N-Alkyl Pyridiniums".
Organic Letters. 23 (17): 6703–6708. doi:10...
- ingestion,
toxic by skin absorption, and corrosive.[citation needed]
Alkynylation Allyl alcohol Propargyl Propargyl chloride NIOSH Pocket Guide to Chemical...
-
expensive alternative reagent is 2-methylbut-3-yn-2-ol,
which after alkynylation is
deprotected with base.
Trimethylsilylacetylene is
commercially available...
-
Ludwig Mond
discovers nickel carbonyl 1899 John
Ulric Nef
discovers alkynylation using sodium acetylides. 1909 Paul
Ehrlich introduces Salvarsan for the...
-
Carboxylate Catalyzed α-
Alkynylation of Amines. Angew. Chem. Int. Ed., 52: 3765–3769. doi:10.1002/anie.201300021 CuI-Catalyzed C1-
Alkynylation of Tetrahydroisoquinolines...
