- An
alarmone is an
intracellular signal molecule that is
produced in bacteria, chloroplasts, and a slim
minority of
archaea reacting to
harsh environmental...
-
Diadenosine tetraphosphate or Ap4A is a ****tive
alarmone,
ubiquitous in
nature being common to
everything from
bacteria to humans. It is made up of two...
-
pentaphosphate and tetraphosphate, also
known as the "magic spot" nucleotides, are
alarmones involved in the
stringent response in
bacteria that
cause the inhibition...
-
conditions and
growth processes. The
stringent response is
signaled by the
alarmone (p)ppGpp, and
modulates transcription of up to 1/3 of all
genes in the...
- (30 July 2019). "Amino
acids as
nutritional factors and (p)ppGpp as an
alarmone of the
stringent response regulate natural transformation in Micrococcus...
-
regulating the RelA
protein and
activating the
synthesis of the
cellular alarmone (p)ppGpp, which, in turn,
triggers the
stringent response and antibiotic...
- environments. SpoT can act as both a
hydrolase and a
synthetase to (p)ppGpp
alarmones in the
stringent response pathway with Mn2+ as its cofactor. When there...
-
superfamily Members share capability to
hydrolyze and/or
synthesize ppGpp alarmones in the
stringent response.
Serpin superfamily Members share a high-energy...
-
synthesis inhibition. c-di-AMP
stimulates the
production of (p)ppGpp, an
alarmone involved in
bacterial stringent response. In
eukaryotic cells, c-di-AMP...
- PMID 26118534.
Jones CP, Ferre-D'Amare AR (Sep 2015). "Recognition of the
alarmone ZMP
through long-distance ****ociation of two RNA subdomains".
Nature Structural...
