- an
infection by a pathogen. They are also
known as
danger signals, and
alarmins because they
serve as
warning signs to
alert the
organism to any damage...
-
Thymic stromal lymphopoietin (TSLP) is an
interleukin (IL)-2-like cytokine,
alarmin, and
growth factor involved in
numerous physiological and pathological...
-
intracellularly as a
nuclear factor and
extracellularly as a cytokine.
Alarmins, also
known as danger-****ociated
molecular patterns (DAMPs), are endogenous...
-
essential for the
normal function of T
helper cells type 2 (Th2 cells) .
Alarmin IL-33 is
constitutively expressed as a
nuclear protein in all epithelial...
-
vitronectin and aggrecan.
Cleavage can
cause cell
death by
anoikis and
release alarmins from the ECM
inducing inflammation.
Fragments of
fibronectin can attract...
- in the
pathophysiology of
several diseases. IL-25, IL-33, and TSLP are
alarmins released from
damaged epithelial cells.
These cytokines mediate the activation...
- Thomas; Feldmann, Marc; Horwood, Nicole; Nanchahal,
Jagdeep (August 2012). "
Alarmins:
awaiting a
clinical response". The
Journal of
Clinical Investigation....
- can also bind some
other ligand to
phagocytose apoptotic cells. HMGB1 is
alarmin and
interacts with DNA
released from
dying cells or
pathogen nucleid acid...
-
activated by
CysLTs and PGD2 in
addition to a
class of
cytokines called alarmins that are
released by
epithelial cells,
including IL-25, IL-33 and thymic...
-
regulatory T cells.
Another factor might be the
production of H.
polygyrus alarmin release inhibitor (A0A3P7XL18), an IL-33-suppressive 26-kDa
Sushi domain...
