- an
infection by a pathogen. They are also
known as
danger signals, and
alarmins because they
serve as
warning signs to
alert the
organism to any damage...
-
Thymic stromal lymphopoietin (TSLP) is an
interleukin (IL)-2-like cytokine,
alarmin, and
growth factor involved in
numerous physiological and pathological...
-
intracellularly as a
nuclear factor and
extracellularly as a cytokine.
Alarmins, also
known as danger-****ociated
molecular patterns (DAMPs), are endogenous...
- hemoglobin, it is also a
potent oxidative molecule. Free heme is also an
alarmin - a
signal of
tissue damage or infection,
which triggers defensive responses...
- rhinitis.
Disruption of the
nasal mucosal epithelial barrier may also
release alarmins (a type of
damage ****ociated
molecular pattern (DAMP) molecule) such as...
-
vitronectin and aggrecan.
Cleavage can
cause cell
death by
anoikis and
release alarmins from the ECM
inducing inflammation.
Fragments of
fibronectin can attract...
- in the
pathophysiology of
several diseases. IL-25, IL-33, and TSLP are
alarmins released from
damaged epithelial cells.
These cytokines mediate the activation...
- Thomas; Feldmann, Marc; Horwood, Nicole; Nanchahal,
Jagdeep (August 2012). "
Alarmins:
awaiting a
clinical response". The
Journal of
Clinical Investigation....
-
activated by
CysLTs and PGD2 in
addition to a
class of
cytokines called alarmins that are
released by
epithelial cells,
including IL-25, IL-33 and thymic...
- damage-****ociated
molecular pattern (DAMP) molecule. DAMPs, also
known as
alarmins, are
recognized by
innate immunity cells by
pattern recognition receptors...
