Definition of Aggresome. Meaning of Aggresome. Synonyms of Aggresome

- In eukaryotic cells, an aggresome refers to an aggregation of misfolded proteins in the cell, formed when the protein degradation system of the cell is...
- were shortened by mutations. Lewy bodies are believed to represent an aggresome response in the cell. When misfolded proteins aggregate, or clump together...
- some are not. Note the following four examples: HDAC6 is ****ociated with aggresomes. Misfolded protein aggregates are tagged by ubiquitination and removed...
- rely on cholesteryl esters derived from LDL. Vimentin plays a role in aggresome formation, where it forms a cage surrounding a core of aggregated protein...
- "The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation". Journal of Cell Science. 115 (Pt 14): 2907–2918. doi:10.1242/jcs...
- overworked. In mammalian cells, these protein aggregates are termed "aggresomes" and they are formed when the cell is diseased. This is because aggregates...
- Kagan, Jonathan C.; Schmidt, Florian I. (2020-09-18). "HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation". Science....
- bodies in neurodegenerative diseases are aggregates of misfolded proteins (aggresomes) and are hallmarks of many of these diseases, including Lewy bodies in...
- perinuclear region of cytoplasm nucleus Lewy body SCF ubiquitin ligase complex aggresome endoplasmic reticulum Golgi apparatus Parkin-FBXW7-Cul1 ubiquitin ligase...
- efficacy of mammalian cells may be limited by epigenetic gene silencing and aggresome formation (recombinant protein aggregation). For mammalian cells, synthesised...