-
Aggrecan (ACAN), also
known as cartilage-specific
proteoglycan core
protein (CSPCP) or
chondroitin sulfate proteoglycan 1, is a
protein that in humans...
- cells,
collagen fibrils, and
aggrecan, a
proteoglycan that
aggregates by
binding to hyaluronan.
Attached to each
aggrecan molecule are glycosaminoglycan...
- family:
aggrecan, brevican, neurocan, and versican.
Lecticans interact with
hyaluronic acid and tenascin-R to form a
ternary complex.
Aggrecan is a major...
-
differentiates into
chondroblasts and
begins secreting the
molecules (
aggrecan and
collagen type II) that form the
extracellular matrix. In all vertebrates...
- brevican, neurocan, versican,
aggrecan, phosphacan, hyaluronan, tenascin-R and
various link proteins. The
CSPGs aggrecan, versican, neurocan, brevican...
-
Aggrecan, the
major proteoglycan in cartilage, has 2316
amino acids...
- tissue)
components including decorin and, in
compressed regions of tendon,
aggrecan,
which are
capable of
binding to the
collagen fibrils at
specific locations...
- For example, in the
cornea and cartilage, the
keratan sulfate domain of
aggrecan consists of a
series of
tandemly repeated hexapeptides with a consensus...
-
aggrecan, a
major proteoglycan of cartilage, brevican, a brain-specific
extracellular matrix protein,
neurocan and versican. The
cleavage of
aggrecan...
- N-acetylglucosamine or N-acetylgalactosamine. The
following CSPGs have been identified:
Aggrecan (CSPG1)
Versican (CSPG2)
Neurocan (CSPG3) CSPG4 (melanoma-****ociated chondroitin...
