-
Aggrecan (ACAN), also
known as cartilage-specific
proteoglycan core
protein (CSPCP) or
chondroitin sulfate proteoglycan 1, is a
protein that in humans...
- cells,
collagen fibrils, and
aggrecan, a
proteoglycan that
aggregates by
binding to hyaluronan.
Attached to each
aggrecan molecule are glycosaminoglycan...
-
differentiates into
chondroblasts and
begins secreting the
molecules (
aggrecan and
collagen type II) that form the
extracellular matrix. In all vertebrates...
- brevican, neurocan, versican,
aggrecan, phosphacan, hyaluronan, tenascin-R and
various link proteins. The
CSPGs aggrecan, versican, neurocan, brevican...
-
Aggrecan, the
major proteoglycan in cartilage, has 2316
amino acids...
- family:
aggrecan, brevican, neurocan, and versican.
Lecticans interact with
hyaluronic acid and tenascin-R to form a
ternary complex.
Aggrecan is a major...
-
contain the link
domain include: the
hyalectans (a
family of proteoglycans):
aggrecan, brevican,
neurocan and versican,
which are
expressed in the CNS; the cartilage...
- For example, in the
cornea and cartilage, the
keratan sulfate domain of
aggrecan consists of a
series of
tandemly repeated hexapeptides with a consensus...
-
include type I
collagen (sp1 site), type IX collagen,
vitamin D receptor,
aggrecan, asporin, MMP3, interleukin-1, and interleukin-6 polymorphisms. Mutation...
-
Versican HS/CS
Testican Perlecan CS
Chondroitin sulfate proteoglycans:
Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5
Platelet factor 4
Structural maintenance...
