Definition of Afucosylate. Meaning of Afucosylate. Synonyms of Afucosylate

- Afucosylated monoclonal antibodies are monoclonal antibodies engineered so that the oligosaccharides in the Fc region of the antibody do not have any fucose...
- 2023). "Understanding antibody-dependent enhancement in dengue: Are afucosylated IgG1s a concern?". PLOS Pathogens. 19 (3): e1011223. doi:10.1371/journal...
- Swiss company GlycArt Biotechnology in order to acquire technology to afucosylate antibodies; one of its products in development was obinutuzumab, which...
- thereby reduce antibody-dependent cellular cytotoxicity. Therefore, afucosylated monoclonal antibodies have been designed to recruit the immune system...
- the infamous human anti-mouse antibody (HAMA). Further advantages show afucosylated recombinant antibodies which are used successfully in the fight against...
- Mogamulizumab, sold under the brand name Poteligeo, is a humanized, afucosylated monoclonal antibody targeting CC chemokine receptor type 4 (CCR4). It...
- million. Pharmaceuticals business The company developed a method to make afucosylated monoclonal antibodies using a CHO cell line in which ****8 has been knocked...
- historically been shown to impact ADCC in adhesion-deficient cells. Afucosylated monoclonal antibodies Hashimoto, G.; Wright, P. F.; Karzon, D. T. (1983-11-01)...
- company of the Swiss Federal Institute of Technology in Zurich to develop afucosylated monoclonal antibodies; GA101 was one of its lead products when it was...
- platform uses a CHO cell line in which ****8 has been knocked out to make afucosylated monoclonal antibodies. GRCh38: Ensembl release 89: ENSG00000033170 –...