-
Afimoxifene, also
known as 4-hydroxytamoxifen (4-OHT) and by its
tentative brand name TamoGel, is a
selective estrogen receptor modulator (SERM) of the...
- respectively,
whereas afimoxifene had 178% and 338% of the
affinity of
estradiol for the ERα and ERβ, respectively. Hence,
afimoxifene showed 25-fold higher...
-
tamoxifen is
metabolized by the CYP2D6
enzyme to
produce endoxifen and
afimoxifene (4-hydroxytamoxifen). Currently,
endoxifen is
approved by
Drugs Controller...
-
afatinib (INN, (USAN)
Afaxin a****ostat (USAN, INN)
afelimomab (INN)
afimoxifene (INN)
aflibercept (USAN, INN))
afloqualone (INN)
afovirsen (INN) AFP-Cide...
- (GSK-9089) GSK-4716 (GW-4716) SLU-PP-332 Antagonists: 4-Hydroxytamoxifen (
afimoxifene)
Bisphenol AF
Diethylstilbestrol ERRγTooltip Estrogen-related receptor...
- 4'-Hydroxynorendoxifen 27-Hydroxycholesterol
Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene Brilanestrant Broparestrol...
- (GSK-9089) GSK-4716 (GW-4716) SLU-PP-332 Antagonists: 4-Hydroxytamoxifen (
afimoxifene)
Bisphenol AF
Diethylstilbestrol ERRγTooltip Estrogen-related receptor...
-
Estrogen Tamoxifen ICI-46,474 3 (0.1–47) 3.33 (0.28–6) 3.4–9.69 2.5 SERM
Afimoxifene 4-Hydroxytamoxifen; 4-OHT 100.1 (1.7–257) 10 (0.98–339) 2.3 (0.1–3.61)...
- 06–16%). 4-Hydroxyclomifene, a
major active metabolite of clomifene, and
afimoxifene (4-hydroxytamoxifen), a
major active metabolite of tamoxifen, show 89–251%...
-
currently under development and in
clinical trials include acolbifene,
afimoxifene (4-hydroxytamoxifen;
metabolite of tamoxifen), elacestrant, enclomifene...
