- The Organizational-
Activational Hypothesis states that
steroid hormones permanently organize the
nervous system during early development,
which is reflected...
-
serotonin 5-HT2B and 5-HT2C receptors. The drug has
roughly the same
activational potencies and
efficacies at the
serotonin 5-HT2A, 5-HT2B, and 5-HT2C...
-
known in humans. It is
unclear why LSD is so potent. The
affinity and
activational potency of LSD at the
human serotonin 5-HT2A
receptor in
vitro is unremarkable...
-
affinity for the
serotonin 5-HT2A
receptor than 5-MeO-DMT,
about the same
activational potency as 5-MeO-DMT at the
receptor in
vitro (EC50Tooltip half-maximal...
-
Salamone JD, Yohn SE, López-Cruz L, San
Miguel N,
Correa M (May 2016). "
Activational and effort-related
aspects of motivation:
neural mechanisms and implications...
- S2CID 4775658.
Salamone JD,
Correa M (January 2024). "The
Neurobiology of
Activational Aspects of Motivation:
Exertion of Effort, Effort-Based
Decision Making...
-
reduces both
inhibitory and
activational aspects of
behavioral control.
Caffeine antagonizes the
effect of
alcohol on the
activational aspect of
behavioral control...
- reported. 1-Methyltryptamine
shows dramatically reduced affinity and
activational potency as well as
reduced efficacy at the
serotonin 5-HT2A receptor...
- with one-third of the
affinity of
oxycodone and 5- to 10-fold
lower activational potency. However,
although a
potent MOR agonist,
noroxycodone poorly...
- and 688% of the
relative activational potency of
testosterone and an EC50 of 0.3 nM and 1,300% of the
relative activational potency of progesterone, with...