-
Abiraterone acetate, sold
under the
brand name
Zytiga among others, is a
medication used to
treat prostate cancer.
Specifically it is used
together with...
- Niraparib/
abiraterone acetate, sold
under the
brand name Akeega, is a fixed-dose
combination anti-cancer
medication used for the
treatment of prostate...
- Δ4-
Abiraterone (D4A; code name CB-7627), also
known as 17-(3-pyridyl)androsta-4,16-dien-3-one, is a
steroidogenesis inhibitor and
active metabolite of...
-
Based on its
known structures while bound to two
steroidal inhibitors,
abiraterone and galeterone, CYP17A1
possesses the
canonical cytochrome P450 fold...
-
abiraterone acetate to
abiraterone by esterases;
abiraterone to Δ4-
abiraterone by 3β-hydroxysteroid dehydrogenase/Δ5-4 isomerase; and Δ4-
abiraterone to...
- orchiectomy),
nonsteroidal antiandrogens, and the
androgen synthesis inhibitor abiraterone acetate.
Castration may be used
alone or in
combination with one of the...
- administration.
First metabolite 3-oxo-Δ4-
abiraterone has more
potent anti-prostate
cancer properties than
abiraterone where galeterone metabolite (3-oxo-Δ4-galaterone)...
-
chemotherapy drugs discovered at the
Institute of
Cancer Research in London.
Abiraterone, a
prostate cancer drug
discovered at the
Institute of
Cancer Research...
-
ketoconazole and the
newer drugs abiraterone acetate, orteronel, galeterone, and seviteronel. CYP17A1 inhibitors, such as
abiraterone acetate, are
primarily used...
-
CYCLONE 3
study compares abemaciclib versus placebo in
combination with
abiraterone and
prednisone in
patients with high-risk, metastatic, hormone-sensitive...
