- Like ADAMs, the name of the
ADAMTS family refers to its
disintegrin and
metalloproteinase activity, and in the case of
ADAMTS, the
presence of a thrombospondin...
- the von
Willebrand factor-cleaving
protease ADAMTS-13. The
plasmapheresis procedure also adds
active ADAMTS-13
protease proteins to the patient, restoring...
- cases. Genomically, ADAMTS13
shares many
properties with the 19
member ADAMTS family, all of
which are
characterised by a
protease domain (the part that...
- Upshaw–Schulman syndrome.
People with this
syndrome generally have 5–10% of
normal ADAMTS-13 activity. A 2024
study suggested that
hereditary TTP is underdiagnosed...
- with
thrombospondin type 1 motif".
Verma P,
Dalal K (Dec 2011). "
ADAMTS-4 and
ADAMTS-5: key
enzymes in osteoarthritis".
Journal of
Cellular Biochemistry...
-
ADAMTS-4
endopeptidase (EC 3.4.24.82, aggrecanase-1) is an enzyme. This
enzyme catalyses the
following chemical reaction Glutamyl endopeptidase; bonds...
- a
disintegrin and
metalloproteinase domain with
throbospondin motifs (
ADAMTS), and
cysteine and
serine proteases are
involved in angiogenesis. This article...
- and disintegrin-like domains,
which are
typical of the
ADAMTS family, but
contains other ADAMTS domains,
including the
thrombospondin type 1 motif. This...
- glioma. ADAMTS4 is the
shortest known ADAMTS,
lacking the C-terminal
domain and is the only non-glycosylated
ADAMTS. It also only has one thrombospondin...
- (2002). "Cloning and
characterization of
ADAMTS-14, a
novel ADAMTS displaying high
homology with
ADAMTS-2 and
ADAMTS-3". J. Biol. Chem. 277 (8): 5756–66....
